Figure 4. RT-PCR revealed abundant KCND2 and KCND3 expression in TRα1-infected cardiac cells, whereas diminished KCND2 and KCND3 levels were detected in TRβ1-expressing myocytes.

KCNA4 expression was reduced in T3-treated control cells. However, KCNA4 mRNA was largely unaffected by exogenous TRα1 or TRß1 overexpression. Representative ethidium bromide-stained agarose gels of RT-PCR products (left) and densitometric analysis of band intensities (right) from at least three independent experiments. *P < 0.05 versus control, **P < 0.05 compared with TRα1, #P < 0.05 compared with TRα1+T3.