Table 1.
SMRs in patients with inflammatory polyarthritis, by sex, length of followup, RA and RF status, and age at symptom onset*
| All-cause mortality | CVD mortality | |||||
|---|---|---|---|---|---|---|
| Observed | Expected | SMR (95% CI) | Observed | Expected | SMR (95% CI) | |
| Sex | ||||||
| Both sexes | 224 | 211.3 | 1.06 (0.93–1.21) | 92 | 73.4 | 1.25 (1.01–1.54) |
| Female | 115 | 117.5 | 0.98 (0.81–1.17) | 46 | 39.3 | 1.16 (0.86–1.56) |
| Male | 109 | 94.0 | 1.16 (0.95–1.40) | 46 | 34.1 | 1.35 (0.99–1.80) |
| Length of followup | ||||||
| 5 years | 86 | 91.3 | 0.94 (0.75–1.16) | 35 | 29.5 | 1.19 (0.83–1.65) |
| 10 years | 187 | 186.9 | 1.00 (0.86–1.15) | 77 | 64.1 | 1.20 (0.95–1.50) |
| Satisfied ACR criteria for RA at baseline | ||||||
| Yes | 123 | 113.1 | 1.09 (0.90–1.30) | 44 | 37.8 | 1.17 (0.85–1.56) |
| No | 101 | 98.4 | 1.03 (0.84–1.25) | 48 | 35.7 | 1.34 (0.99–1.78) |
| RF status at baseline | ||||||
| Positive | 78 | 55.7 | 1.40 (1.11–1.75) | 38 | 19.0 | 2.00 (1.41–2.74) |
| Negative | 114 | 129.6 | 0.88 (0.73–1.06) | 43 | 46.6 | 0.92 (0.67–1.24) |
| RF status at baseline: findings at 5-year followup | ||||||
| Positive | 33 | 23.8 | 1.39 (0.96–1.95) | 15 | 7.8 | 1.93 (1.08–3.19) |
| Negative | 42 | 53.3 | 0.79 (0.57–1.07) | 16 | 17.8 | 0.90 (0.51–1.46) |
| RF status at baseline: findings at 10-year followup | ||||||
| Positive | 63 | 49.2 | 1.28 (0.98–1.64) | 33 | 16.5 | 2.00 (1.37–2.80) |
| Negative | 94 | 113.4 | 0.83 (0.67–1.01) | 33 | 40.4 | 0.82 (0.56–1.15) |
| Age at symptom onset | ||||||
| Entire cohort | ||||||
| <55 years | 20 | 18.9 | 1.06 (0.64–1.63) | 9 | 5.1 | 1.75 (0.80–3.32) |
| ≥55 years | 204 | 192.6 | 1.06 (0.92–1.22) | 83 | 68.3 | 1.21 (0.97–1.51) |
| RF-positive patients | ||||||
| <55 years | 11 | 4.38 | 2.51 (1.25–4.48) | 7 | 1.3 | 5.58 (2.24–11.50) |
| ≥55 years | 67 | 51.4 | 1.30 (1.01–1.66) | 31 | 17.7 | 1.75 (1.19–2.48) |
*
SMRs = standardized mortality ratios; RA = rheumatoid arthritis; RF = rheumatoid factor; 95% CI = 95% confidence interval; CVD = cardiovascular disease; ACR = American College of Rheumatology.