Table 3.

Multivariate predictors of all-cause and CVD mortality, by length of followup^*

	HR (95% CI)
	5-year followup		10-year followup
Variable	All-cause mortality	CVD mortality	All-cause mortality	CVD mortality
Age at symptom onset (10-year intervals)	2.71 (2.17–3.39)	3.89 (2.77–5.46)	2.50 (2.15–2.91)	2.94 (2.37–4.46)
Sex	2.28 (1.44–3.60)	1.64 (0.89–3.00)	2.19 (1.59–3.02)	2.08 (1.38–3.16)
Delay to presentation in months (tertiles)
Group 1 (0–2.9 months)	1.00	†	†	†
Group 2 (3.0–7.9 months)	0.52 (0.30–0.92)	†	†	†
Group 3 (8.0–54.0 months)	0.92 (0.53–1.60)	†	†	†
RF-positive at baseline	1.59 (1.01–2.51)	2.95 (1.58–5.50)	1.45 (1.01–2.05)	1.99 (1.31–3.01)
Nodules present at baseline	2.19 (1.18–4.05)	2.46 (0.91–6.71)	2.12 (1.33–3.37)	2.28 (1.17–4.46)
HAQ score at baseline ≥1.5	1.17 (0.87–1.60)	†	1.29 (1.03–1.62)	†

^*HR = hazard ratio; HAQ = Health Assessment Questionnaire (see Table 1 for other definitions).

^†Baseline variable subsequently shown to not be a predictor in the multivariate model.