Table 1.
Study details and subject characteristics
| Study | Study medication (mg t.i.d.) | Subjects (n = 99) | Age (years) | Height (cm) | Weight (kg) |
|---|---|---|---|---|---|
| 1* | Placebo | 6 | 34.5 | 179.8 | 76.0 |
| 50 | 7 | 29.0 | 184.1 | 80.1 | |
| 100 | 7 | 31.4 | 187.0 | 82.1 | |
| 150 | 7 | 30.1 | 177.7 | 72.1 | |
| 2* | Placebo | 9 | 32.6 | 177.7 | 76.2 |
| 150 | 9 | 34.4 | 181.9 | 82.0 | |
| 300 | 9 | 32.9 | 180.3 | 78.2 | |
| 120 mg t.i.d. Orlistat | 9 | 35.3 | 180.1 | 81.6 | |
| 3* | Placebo | 9 | 34.1 | 180.0 | 79.3 |
| 60 | 9 | 31.2 | 180.6 | 78.1 | |
| 120 | 9 | 33.9 | 181.2 | 82.0 | |
| 240 | 9 | 36.7 | 178.0 | 77.5 | |
| Mean | – | 33.1 | 180.6 | 78.9 |
*
Study 1: ATL962/012/CL (564/ALZ); Study 2: ATL962/080/CL (605/ALZ); Study 3: ATL962/081/CL (657/ALZ).