Figure 5. MPA treatment efficiently kills B-CLL cells.

Leukemic B-cells isolated from CLL patients (n = 14) were treated with either the apoptotic inducers TRAIL (500 ng/ml) or CD95L (500 ng/ml) or with MPA (10 µg/ml) for 72 hours. Then total cell death was quantified using the metabolic assay MTT (total cell death). Statistical analysis was performed using a non-parametric Mann-Whitney two sample ranksum test (n = 14). N.S means non-significant and ** P≤0.01.