Table 1.
Expression of immunocytochemical markers in the CCC of the colon submucosa including some histological staining
| Marker | Clear cells |
| CD3 (T cell) | Negative |
| CD4 (T cell) | Negative |
| CD22 (B cell) | Negative |
| CD34 (precursor cell) | Negative |
| CD31 (Endothelial) | Negative |
| CD68 (Macrophages) | +++ Strongly positive |
| PCNA-proliferation antigen | Negative2 |
| Ki67 mitotic activity | Negative1 |
| Chromogranin | Negative |
| Synaptophysin | Negative |
| Naurofilament | Negative |
| Actin | Negative |
| P53 mutations | Negative |
| GFAP glial marker | Negative |
| TNF alpha | Negative |
| IL2 | Negative |
| Mucicarmin | Negative |
| PAS | Strong positive |
| PAS diastase | Digested |
| Osmium tetraoxide | Positive |
1
1-3 per crypt;
2
Positive in the cryptic epithelium.