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PITX1 expression in normal gastric mucosa and gastric cancer tissue samples (x 400). A: Normal gastric mucosa, PITX1 positive; B: Well-differentiated gastric carcinoma, PITX1 positive; C: Gastric carcinoma with lymph node metastasis, PITX1 positive; D: Signet-ring-cell carcinoma (poor-differentiated), PITX1 negative; E: Intestinal metaplasia, PITX1 negative; F: Atypical hyperplasia, PITX1 positive.
