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Three proposed models for the genesis of CNS cell components. (A) Model1, NRP/GRP model; (B) Model2, MNOP model; (C) Model3, Sequential model. NRPs, neuronal restricted progenitors; GRPs, glial restricted progenitors; MNOP, motoneuron and oligodendrocyte common progenitor; NA, neuron and astrocyte common progenitor; OPC, oligodendroctye precursor; pA, astrocyte precursor; pM, motoneuron precursor.
