Table 1. Scrapie transmission data.
n/no = No. of hamsters diagnosed with scrapie/no. of hamsters inoculated. Ref, Reference sample.
Strain | Inoculum | n/no | IP★ | P value† |
---|---|---|---|---|
DY | Control | 6/7 | 259±59 | Ref |
PrP27–30 | 8/8 | 246±34 | 0.897 | |
Sonicated | 5/8 | 219±16 | 0.518 | |
139H | Control | 7/7 | 106±12 | Ref |
PrP27–30 | 7/8 | 150±73‡ | 0.158 | |
Sonicated | 7/7 | 110±14 | 0.700 | |
Sc237 | Control | 8/8 | 106±26 | Ref |
PrP27–30 | 7/8 | 110±21 | 0.559 | |
Sonicated | 8/8 | 116±44 | 0.787 |
Mean incubation period (IP) of scrapie sick animals ± SD.
Mann–Whitney test comparing incubation period for each inoculum against controls within each strain.
The large SD in this group was attributable to two animals with incubation times of 214 and 288 days; excluding these animals, the incubation period of the remaining hamsters in this group was 110 ± 5 days.