TABLE 3.

sav homologues in phage mutants insensitive to AbiV

Phage	Mean EOP ± SDa	Mutant gene(s)	No. of amino acids in gene product	Nucleotide mutation(s)b	Amino acid mutation(s) or effect(s)
p2.1	1.1 ± 0.4	orf26	128	Deletion of 56 nt, GCT→ACT, GCT→GAT	A45T, A60D
p2.2	0.9 ± 0.3	orf26	128	GGA→TGA	G65→stop
p2.3	0.7 ± 0.4	orf26	128	RBS mutation: GGATTTGGGGT
p2.4	0.9 ± 0.1	orf26	128	ATG→ATA	M1I
p2.5	0.9 ± 0.1	orf26	128	GAA→TAA	E19→stop
p2.6	1.4 ± 0.4	orf26, orf28	128, 61	GGA→TGA, GAA→TAA	G65→stop, E30→stop
p2.7	1.1 ± 0.3	orf26	128	CAG→TAG	Q37→stop
p2.8	0.9 ± 0.2	orf26	128	GAA→TAA	E16→stop
p2.9	0.8 ± 0.1	orf26	128	RBS mutation: GGATTGGTGGT
p2.10	0.9 ± 0.1	orf26	128	RBS mutation: GGATTGCGGGT
p2.11	0.6 ± 0.3	orf26	128	RBS mutation: GGATTTGGGGT
sk1.1	0.8 ± 0.2	orf26	128	ATG→ATA	M1I
jj50.1	0.8 ± 0.2	orf25	128	GGA→TGA	G65→stop
P008.1	1.2 ± 0.4	orf33	119	TGG→TAG	W33→stop
bIL170.1	1.1 ± 0.2	e24	130	GAA→TAA	E58→stop
c2.1	1.0 ± 0.3	e11	122	ACT→CCT	T48P
bIL67.1	0.8 ± 0.2	orf8	116	TAC→TAA	Y10→stop

^aEOP values are relative to the level of phage p2 plaque formation on L. lactis subsp. cremoris MG1363 (or MB112), which is set at 1.0.

^bMutations in the putative RBS of sav, GGATTGGGGGT, are underlined and shown in bold.