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Circulating antibody levels from groups of Wistar Kyoto (WKY) rats (n = 6) immunized with alpha 3 chain of type IV collagen [α3(IV)NC1] or the five 15-mer overlapping peptides, directed towards: (a) α3(IV)NC1 and (b) pCol(24–38). Results shown represent the mean ± standard deviation of each group at week 6 after immunization. *P < 0·01; **P < 0·005, pCol(24–38) immunized versus Freund's complete adjuvant (FCA) alone. Each experiment was performed twice.
