Fig. 2.

Glomerular fibrinogen staining in mice treated with Shiga toxin (Stx). (a) Glomerular staining in a wild-type mouse treated with 200 ng Stx-2 in combination with lipopolysaccharide (LPS). (b) Glomerular staining in a wild-type mouse subjected to serum nephrotoxic nephritis, an experimental model of immune complex-mediated glomerular disease characterized by glomerular inflammation and thrombosis. Marked staining is seen in the positive control (b), while staining is completely absent in the animal treated with Stx-2 and LPS.