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. Author manuscript; available in PMC: 2009 Apr 30.

Published in final edited form as: Mech Ageing Dev. 2007 Nov 4;128(11-12):706–716. doi: 10.1016/j.mad.2007.10.013

Relationship between SOD2 expression and demographic parameters. Q= Sod2ⁿ²⁸³^/wk, R= Sod2ⁿ²⁸³^/+, S= Sod2^wk/wk, T= KG06854R and U= Sod2^+/+; P{Sod2^+/+}. (A) A power law relationship was observed when the demographic rate of aging (parameter b from WinModest) was plotted versus percent SOD2 expressed. R² = 0.9636. Inset shows projected rate of demographic aging as a function of percent SOD2 expression, indicating that a marginal decrease in the rate of demographic aging will occur with progressively increased levels of SOD2 expression. (B) Log mean lifespan versus Log SOD2 expression describes a straight line, indicating that the percent change in mean lifespan will eventually plateau after a certain level of SOD2 expression is achieved (inset).

Relationship between SOD2 expression and demographic parameters. Q= Sod2ⁿ²⁸³^/wk, R= Sod2ⁿ²⁸³^/+, S= Sod2^wk/wk, T= KG06854R and U= Sod2^+/+; P{Sod2^+/+}. (A) A power law relationship was observed when the demographic rate of aging (parameter b from WinModest) was plotted versus percent SOD2 expressed. R² = 0.9636. Inset shows projected rate of demographic aging as a function of percent SOD2 expression, indicating that a marginal decrease in the rate of demographic aging will occur with progressively increased levels of SOD2 expression. (B) Log mean lifespan versus Log SOD2 expression describes a straight line, indicating that the percent change in mean lifespan will eventually plateau after a certain level of SOD2 expression is achieved (inset).