Table 3 Meta‐analyses of randomised controlled trials of inhaled nitric oxide in preterm babies: overview of outcomes.

Outcome	Relative risk (95% CI)	Absolute risk reduction (95% CI)	Number needed to treat
Early prophylactic treatment
Severe IVH/PVL	0.70 (0.53 to 0.91)	–0.07 (−0.12 to −0.02)	14
BPD at 36 weeks	0.92 (0.83 to 1.02)
Death	0.77 (0.61 to 0.98)	−0.06 (−0.11 to −0.01)	17
Death or BPD	0.92 (0.85 to 0.99)	−0.06 (−0.12 to 0)	17
Early rescue treatment
Severe IVH/PVL	1.02 (0.80 to 1.31)
BPD at 36 weeks	0.93 (0.78 to 1.09)
Death	1.05 (0.89 to 1.22)
Death or BPD	0.93 (0.87 to 1.00)
Late treatment
Severe IVH/PVL	No data available
BPD at 36 weeks	0.90 (0.78 to 1.04)
Death	1.06 (0.64 to 1.74)
Death or BPD	0.90 (0.80 to 1.02)

BPD, bronchopulmonary dysplasia; IVH/PVL, intraventricular haemorrhage/periventricular leucomalacia.