Table 2 Long‐term outcome in three patients with fetal exposure to enalapril.
| Patient | |||
|---|---|---|---|
| A | B | C | |
| Age, years | 18.1 | 12.8 | 6.4 |
| GFR, ml/min/1.73 m2* | 60 | 96 | 64 |
| 24‐h proteinuria, g | 1.5 | <0.06 | 0.18 |
| Renal ultrasound† | Small, bright kidneys | Normal | Small, bright kidneys |
| 24‐h ABPM MAP, mm Hg‡ | 100 (non‐dipper) | 77 (non‐dipper) | 76 (dipper) |
| Haemoglobin, g/l§ | 182 | 152 | 150 |
| Erythrocytes T/l (normal <5) | 6.2 | 5.0 | 5.6 |
| Erythropoietin U/l (normal 8–22) | <5 | 10 | 8.7 |
ABPM, ambulatory blood pressure; GFR, glomerular filtration rate; MAP, mean arterial pressure.
*Normal >80ml/min/1.73 m2.
†“Small” indicates renal length < height related third centile.
‡MAP, 95th centile: 97 (A, B), 87 (C).
§Normal <160 g/l (A, B), <140 g/l (C)