Skip to main content
. 2007 Apr 25;92(6):F454–F458. doi: 10.1136/adc.2006.094359

Table 1 Infant demographics, risk factors and incidence of Candida sepsis before and after the implementation of the antifungal prophylaxis guideline.

Before guideline implementation After guideline implementation p Value
Number of medical records available 110 102
Gestational age (weeks), median (range) 28 (24–36) 28 (23–34) >0.9
Birth weight (g), median (range) 1040 (380–1495) 980 (429–1490) 0.3
Number eligible for prophylaxis, n/N (%) 33/110 (31) 31/102 (30) >0.9
Cephalosporin use, n/N (%) 18/110 (16) 14/102 (14) >0.9
Antibiotic >10 days, n/N (%) 23/110 (21) 19/102 (19) >0.9
Fungal colonisation + central venous catheter, n/N (%) 6/110 (6) 6/102 (6) >0.9
Culture proven Candida sepsis in eligible babies 6/33 0/31 0.03
Culture proven and probable Candida sepsis in eligible babies 6/33 1/31 0.1
Total died 7/33 3/31 0.2
Died Candida sepsis 4/33 0/31 0.11