Table 3 Perinatal outcome by study group. Values are n (%).
| Non‐SGA both | SGA population only | SGA customised only | SGA both | p Value | ||
|---|---|---|---|---|---|---|
| Intermediate groups | All groups | |||||
| Elective CS‡ | 679 (5.9) | 20 (9.9) | 47 (8.5) | 141 (10.9) | 0.54* | <0.001* |
| Emergent CS for distress¶ | 304 (26) | 6 (3) | 24 (4.4) | 84 (6.6) | 0.4* | <0.001* |
| Metabolic acidosis§ | 54 (0.5) | 1 (0.5) | 9 (1.7) | 19 (1.5) | 0.3† | <0.001* |
| Five‐minute Apgar <7‡ | 71 (0.6) | 2 (1) | 4 (0.7) | 17 (1.3) | 0.66† | 0.035* |
| Perinatal death | 65 (0.6) | 2 (1) | 10 (1.8) | 22 (1.7) | 0.74† | <0.001* |
| OR (95% CI) | – | 1.8 (0.4 to 7.2) | 3.2 (1.6 to 6.2) | 3 (1.9 to 4.9) | ||
| Stillborns | 51 (0.4) | 2 (1) | 10 (1.8) | 17 (1.3) | 0.74† | <0.001* |
| Neonatal death‡ | 14 (0.1) | 0 (0) | 0 (0) | 5 (0.4) | – | 0.071* |
| Neurological morbidity‡ | 72 (0.6) | 2 (1) | 11 (2) | 17 (1.3) | 0.53† | <0.001* |
| OR (95% CI) | 1.6 (0.4 to 6.5) | 3.2 (1.7 to 6.1) | 2.1 (1.3 to 3.6) | |||
| Seizures‡ | 20 (0.2) | 1 (0.5) | 2 (0.4) | 5 (0.4) | 1† | 0.25* |
| Intraventricular haemorrhage‡ | 13 (0.1) | 1 (0.5) | 1 (0.2) | 6 (0.5) | 0.46† | 0.012* |
| Periventricular leucomalacia‡ | 3 (0) | 0 (0) | 1 (0.2) | 0 (0) | 1† | 0.2* |
| Hypoxic‐ischaemic encephalopathy‡ | 37 (0.3) | 0 (0) | 2 (0.4) | 8 (0.6) | 1† | 0.29* |
| Abnormal electroencephalogram‡ | 45 (0.4) | 1 (0.5) | 6 (1.1) | 7 (0.5) | 0.68† | 0.1* |
| Non‐neurological morbidity‡ | 53 (0.5) | 1 (0.5) | 20 (3.6) | 17 (1.3) | 0.02* | <0.001* |
| OR (95% CI) | – | 1.1 (0.1 to 7.8) | 8 (4.8 to 13.6) | 2.9 (1.7 to 5) | ||
| Prolonged NICU stay‡ | 46 (0.4) | 1 (0.5) | 17 (3.1) | 16 (1.2) | 0.05† | <0.001* |
| Hypoglycaemia‡ | 112 (1) | 0 (0) | 14 (2.5) | 42 (3.3) | 0.03† | <0.001* |
| Necrotising enterocolitis‡ | 4 (0) | 0 (0) | 1 (0.2) | 2 (0.2) | 1† | 0.16* |
| Acute renal or cardiac failure‡ | 13 (0.1) | 0 (0) | 2 (0.4) | 3 (0.2) | 1† | 0.29* |
CS, caesarean section; NICU, neonatal intensive care unit; OR, odds ratio; SGA, small for gestational age.
*Pearson‐χ2; †exact Fisher's test.
‡Stillborns excluded; ¶Stillborns and cases with elective caesarean section excluded; §Stillborns and cases with unavailable umbilical cord sample at birth excluded (n = 528).