Table 1 Clinical details and follow‐up results of four cases (three previously published1), who underwent unilateral nephrectomy at a very young age for hypertension.
| Case | Sex | Function (%)* | Age in years | Growth SD scores† | Systolic blood pressure | UA/UC‡ (normal ⩽3) | GFR¶ | Clinical information | ||
|---|---|---|---|---|---|---|---|---|---|---|
| At surgery | At follow‐up | Height | Weight | |||||||
| Reference 1 | Boy | 24 | 0.2 | 16.4 | −0.17 | 2.1 | 124 | 0.3 | 92 | Cardiac failure day 3; ventricular hypertrophy |
| Case 1 | Left kidney small, with patchy nephrogram | |||||||||
| Histological picture: areas of ischaemia | ||||||||||
| Reference 1 Case 2 | Boy | 14 | 2.5 | 19.0 | 1.07 | 1.93 | 120 | 8.3 | 92 | Failure to thrive at 1 year, with cardiac failure and hypertrophic ventricles |
| Left renal artery stenosis | ||||||||||
| Reference 1 Case 3 | Girl | 23 (0 after captopril) | 0.9 | 16.9 | 1.32 | −0.13 | 122 | 2.0 | 111 | Failure to thrive; cardiac failure and ventricular hypertrophy at 10 months |
| Right renal artery stenosis | ||||||||||
| Case 4 | Boy | 27 | 0.05 | 4.9 | −0.90 | −0.17 | 86 | 1.0 | 105 | Respiratory distress and cardiac failure at 2 weeks; imaging suggested a thromboembolus from the umbilical artery catheter |
| Hypertension difficult to control medically, so urgent right nephrectomy; infarction confirmed | ||||||||||
*Percentage of the total renal function supplied by the kidney that was removed, estimated from a dimercaptosuccinic acid (DMSA) scan.
†Growth standard deviation scores.
‡Early morning urine albumin (UA):creatinine (UC) ratio, mg/mmol.2
¶Glomerular filtration rate, ml/min/1.73m2, estimated from the plasma creatinine concentration and height.3