Table 2 Bivariable logistic regression analysis of risk factors and outcomes associated with cases of S marcescens sepsis versus uninfected controls.
Characteristic | S marcescens (n = 25) | Uninfected controls (n = 50) | OR (95% CI)* | p† |
---|---|---|---|---|
Host and perinatal factors | ||||
Vaginal delivery | 10 (40) | 19 (38) | 1.09 (0.41 to 2.91) | 0.87 |
Maternal antibiotic use | 9 (36) | 15 (30) | 1.31 (0.48 to 3.63) | 0.60 |
Preterm labor | 16 (64) | 24 (48) | 1.93 (0.72 to 5.17) | 0.25 |
Prolonged rupture of membranes | 2 (8) | 5 (10) | 0.78 (0.14 to 4.35) | 0.80 |
Maternal fever | 1 (4) | 2 (4) | 1.00 (0.09 to 11.59) | 0.96 |
Chorioamnionitis | 3 (12) | 0 | 0.03 | |
Procedures and conditions | ||||
Intubated | 13 (52) | 22 (44) | 1.38 (0.53 to 3.61) | 0.51 |
Prolonged intubation | 11 (44) | 15 (30) | 1.83 (0.68 to 4.96) | 0.23 |
Surgery | 12 (48) | 7 (14) | 5.67 (1.81 to 17.37) | <0.01 |
Urinary catheter | 1 (4) | 1 (2) | 2.04 (0.12 to 34.07) | 0.61 |
CVC | 20 (80) | 24 (48) | 4.33 (1.41 to 13.36) | 0.01 |
TPN | 14 (56) | 31 (62) | 0.78 (0.29 to 2.07) | 0.62 |
Intralipids | 13 (52) | 31 (62) | 0.66 (0.25 to 1.75) | 0.41 |
H2‐blockers | 11 (44) | 31 (62) | 0.48 (0.18 to 1.28) | 0.14 |
Clinical outcome | ||||
Death | 11 (44) | 1 (2) | 38.50 (4.57 to 324.47) | 0.001 |
†Bivariable logistic regression
*OR: odds ratio; CI: confidence interval