Table 3 Bivariable logistic regression analysis of risk factors and outcomes associated with cases of S marcescens bacteremia versus E Coli‐bacteremic controls.
Characteristic | S marcescens (n = 25) | E Coli (n = 50) | OR (95% CI)* | p† |
---|---|---|---|---|
Host and perinatal factors | ||||
Vaginal delivery | 10 (40) | 14 (28) | 1.40 (0.82 to 2.40) | 0.19 |
Maternal antibiotic use | 9 (36) | 27 (54) | 0.48 (0.18 to 1.29) | 0.14 |
Preterm labor | 16 (64) | 36 (72) | 0.69 (0.25 to 1.92) | 0.48 |
Prolonged rupture of membranes | 2 (8) | 13 (26) | 0.25 (0.05 to 1.20) | 0.06 |
Maternal fever | 1 (4) | 7 (14) | 0.26 (0.03 to 2.21) | 0.21 |
Chorioamnionitis | 3 (12) | 10 (20) | 0.55 (0.14 to 2.19) | 0.39 |
Procedures and conditions | ||||
Intubated | 13 (52) | 21 (42) | 1.50 (0.57 to 3.93) | 0.41 |
Prolonged intubation | 11 (44) | 6 (12) | 5.76 (1.80 to 18.42) | <0.01 |
Surgery | 12 (48) | 13 (26) | 2.63 (0.96 to 7.20) | 0.06 |
Urinary catheter | 1 (4) | 1 (2) | 2.04 (0.12 to 34.07) | 0.61 |
CVC | 20 (80) | 17 (34) | 7.77 (2.48 to 24.31) | <0.001 |
TPN | 14 (56) | 14 (28) | 3.27 (1.20 to 8.92) | 0.02 |
Intralipids | 13 (52) | 13 (26) | 3.08 (1.13 to 8.44) | 0.03 |
H2‐blockers | 11 (44) | 10 (20) | 3.14 (1.10 to 8.99) | 0.03 |
Repeat positive blood culture | 13 (52) | 12 (24) | 3.43 (1.24 to 9.50) | 0.02 |
Presenting signs and symptoms | ||||
Apnea | 9 (36) | 23 (46) | 0.66 (0.25 to 1.77) | 0.41 |
Bradycardia | 7 (28) | 16 (32) | 0.83 (0.29 to 2.38) | 0.72 |
Hypoglycemia | 3 (12) | 5 (10) | 1.23 (0.27 to 5.61) | 0.79 |
Hyperglycemia | 8 (32) | 18 (36) | 0.84 (0.30 to 2.32) | 0.73 |
Hypothermia | 11 (44) | 17 (34) | 1.53 (0.57 to 4.08) | 0.40 |
Hyperthermia | 8 (32) | 7 (14) | 2.89 (0.91 to 9.22) | 0.07 |
Neutropenia | 1 (4) | 6 (12) | 0.31 (0.04 to 2.69) | 0.29 |
Clinical outcome | ||||
Meningitis | 6 (24) | 8 (16) | 1.66 (0.51 to 5.45) | 0.41 |
Death | 11(44) | 14(28) | 2.02 (0.74 to 5.51) | 0.17 |
Sepsis‐related death | 6 (24) | 11 (22) | 1.12 (0.36 to 3.49) | 0.85 |
†Bivariable logistic regression
*OR: odds ratio; CI: confidence interval