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. 2007 Mar;92(2):F108–F112. doi: 10.1136/adc.2006.099499

Table 3 Developmental performance and genotype.

Developmental and subscale quotients GG genotype C allele Mean difference (95% CI) p Value
Griffith's DQ 97.6 (1.5) 92.7 (1.7) 4.9 (−9.7 to −0.25) 0.039
 Locomotor 92.9 (1.4) 91.4 (1.9) 1.5
 Personal‐social 103.6 (1.7) 96.2 (1.7) 7.4
 Hearing and speech 94.9 (2.4) 88.8 (2.4) 6.1
 Hand eye development 93.8 (1.4) 89.3 (1.9) 4.5
 Performance 102.9 (1.8) 97.6 (2.5) 5.3
GCA 100.9 (1.7) 94.3 (2.2) 6.6 (−12.4 to −0.7) 0.028
 Verbal subscale 103.7 (1.5) 94.0 (3.3) 9.7
 Non‐verbal subscale 100.0 (1,7) 95.3 (2.4) 4.7
 Spatial subscale 98.9 (1.8) 93.3 (2.2) 5.6

DQ, developmental quotient; GCA, general cognitive ability.

207 had follow up to 2 years and 156 had follow‐up to 5½ years.

Values are mean (SEM).