Figure 3. The regulatory pathways of E2F target genes in cancer cell cycle based on the dynamic regulatory modeling in Table 1.

The related genes are represented as gray ovals and the regulatory abilities of the related regulators implying different degree of influence are converted into red-colored lines as positive regulations (activations) and black-colored lines as negative regulations (inhibitions) for each target gene. These regulatory pathways could be integrated as the regulatory network of cancer cell cycle in Figure 4.