. Author manuscript; available in PMC: 2010 Feb 1.

Published in final edited form as: Anesth Analg. 2009 Feb;108(2):399–406. doi: 10.1213/ane.0b013e31818cdb13

Table 2.

Plasma Cytokine Levels Following Myocardial Ischemia-Reperfusion in the Mouse: Efects of Aprotinin (pg/mL)

	TNF-α	IL-6	IL-10
Referent Controls	3 ±1	10 ±11	3 ±1
I/R Vehicle	25 ±7^*	1700 ±703^*	18 ±8^*

I/R 2×10⁴ KIU/kg	25 ±7^*	1250 ±755^*	19 ±11^*

I/R 4×10⁴ KIU/kg	15 ±5^*⁺	1733 ±1486^*	13 ±7^*

I/R 8×10⁴ KIU/kg	14 ±4^*⁺	1951 ±1340^*	13 ±8^*

p<0.05 vs pooled referent control

⁺

p<0.05 vs Vehicle.

Data are reported as Mean ± SD; Pooled Referent Control Samples (n=23) – see text; I/R groups – Vehicle (n=10), 2×10⁴ KIU/kg (n=11), 4×10⁴ KIU/kg (n=10), 8×10⁴ KIU/kg (n=10)