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. 2009 Feb 23;30(5):869–878. doi: 10.1093/carcin/bgp051

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© The Author 2009. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

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Fig. 6. — FOXO1A, but not FRAP1, is a target of PI3K/Akt signaling in Pten^{tm1Hwu/tm1Hwu};Ctnnb1^tm1Mmt/+;Amhr2^{tm3(cre)Bhr/+} GCTT. Western blot analysis of AKT, p-AKT(S473), FOXO1A, p-FOXO1A(S256), FRAP1 and p-FRAP1(S2448) expression in Pten^{tm1Hwu/tm1Hwu};Ctnnb1^tm1Mmt/+;Amhr2^{tm3(cre)Bhr/+} GCTT (lanes 1–3), Ctnnb1^tm1Mmt/+;Amhr2^{tm3(cre)Bhr/+} testis (lanes 4–6) and Pten^{tm1Hwu/tm1Hwu};Ctnnb1^tm1Mmt/+ (control) testis (lanes 7–9). ACTB was used as a housekeeping control gene.