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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: IUBMB Life. 2009 May;61(5):496–503. doi: 10.1002/iub.185

Figure 1. Diagram summarizing the developmental stages of GCPs in neonates.

Figure 1

GCPs undergo clonal expansion (proliferation) in the outer part of the EGL. Once they exit the cell cycle, they move to the inner part of the EGL where they tangentially migrate and extend their processes. They then turn 90° angle, grab onto a Bergmann glial process and radially migrate throughout the molecular layer (ML) to the Purkinje cell layer (PC). In the outer EGL and other layers, GCPs express functional kainate receptors (kainateRs). It is unclear whether they express mGluRs. We show in this review article that GCPs also express functional GABAARs. In the inner EGL, they start expressing NMDA and AMPA receptors (NMDAR and AMPARs, respectively).