Graphical illustration of phantoms (transverse and axial views) and their placement within the 25-cm axial FOV (indicated by the light gray shaded regions in the axial views) of the simulated scanner. Hot lesion phantom (left three images): 25-cm long phantom with 27 (and 35) cm diameter with hot spherical lesions in two different slices. The central slice (slice A) contained three sets each of 22, 17, 13, and 10-mm diameter spheres, all placed at a radial distance 7 cm from the transverse center. An off-center slice (slice B) at an axial position one-quarter of the axial FOV from the center (6.25 cm) contained eight uniformly distributed 10-mm diameter spheres, again at a radial position of 7 cm. The activity uptake ratio for the hot spheres was 4:1 with respect to the background. Short phantom (right image): 11-cm long cylindrical phantom with 35-cm diameter centered in the scanner. The phantom contained eight 10-mm hot spheres (same configuration as slice B in the hot lesion phantom); the edges of the spheres were located about 15 mm from the axial edge of the phantom.