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. 2008 Dec;66(6):838–845. doi: 10.1111/j.1365-2125.2008.03290.x

Table 2.

Influence of action suggested by participants (n = 1000) after child is prescribed a medicine that has not been fully tested for use in children, on participants’ offering their child's participation in a clinical trial

Participant categorization
Assumed health condition Change the medicine*n (%) Accept the medicinen (%) P value Chi squared test
Child suffering from a life threatening condition 195 (48.3) 224 (37.6) 0.001
Child suffering from a chronic but not life threatening condition 80 (19.8) 89 (14.9) 0.044
Child suffering from a minor condition 111 (27.5) 80 (13.4) <0.001
Child in hospital 168 (41.6) 117 (19.6) <0.001
Child in good health 28 (6.9) 11 (1.8) <0.001
*

Ask the doctor to change the medicine to one that has been fully tested and licensed for use in children.

Combined categories: Simply accept that the doctor knows best and use the medicine in the child but check carefully for side-effects.