Table 3.
Summary of stepwise model building
| Model | Effect | ΔOBJF* | P-value |
|---|---|---|---|
| BASE | No covariates included | – | – |
| INTERMEDIATE | TPMT mutations on FM3 | −8.69 | <0.005 |
| FULL | TPMT mutations on FM3 | −12.85 | <0.0005 |
| BSA on CL6-TGNs |
Change in OBJF in comparison to preceding model. A ΔOBJF ≥6.63 is statistically significant at P < 0.01 for 1 degree of freedom. TPMT, thiopurine methyltransferase; BSA, body surface area.