Table 2.
Stepwise logistic regression analysis of variables associated with seizures after citalopram overdose. Variables not retained in the model were male, acute ethanol co-ingestion, chronic ethanol consumption, co-ingestion of benzodiazepines, co-ingestion of other drugs, activated charcoal administration, hyponatraemia and QTc
| Variables included | Coefficient | Odds ratio (95% CI) | P value |
|---|---|---|---|
| Constant | −1.02 | ||
| Age (10 years increment) | −0.54 | 0.6 (0.3 to 1.0) | 0.042 |
| Citalopram dose (100 mg increment) | 0.09 | 1.1 (1.0 to 1.2) | 0.036 |
| Co-ingested tricyclic antidepressant or venlafaxine | 2.44 | 15.1 (3.0 to 75.3) | 0.001 |
| Co-ingested other drugs* | −1.87 | 0.1 (0.0 to 0.7) | 0.013 |
Excluding benzodiazepines.