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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Coord Chem Rev. 2009;253(11-12):1649–1660. doi: 10.1016/j.ccr.2009.01.032

Figure 4.

Figure 4

The chemical structures of naturally occurring and synthetic proteasome inhibitors are depicted. Lactacystin is a natural product derived from a microbial metabolite, EGCG is green tea polyphenol, and bortezomib is a synthetic dipeptide boronic acid analogue.