Figure 3.

Early and late cell cycle genes are overrepresented in the best separating cell cycle gene set. The density plot compares the distribution of different cell cycle gene sets. x-axis: cell cycle states (from 0 to 99; complete cell cycle). y-axis: relative frequencies. Black line: density of all mapped cell cycle genes of de Lichtenberg et al (de Lichtenberg et al. 2005) in the data set. The area under this line is coloured for easier comparison. Blue line: Optimal separating subset of cell cycle genes (77 spots). Two peaks in the early and late cell cycle states show cell cycle gene expression differences between the subgroups ABC and GCB.