Table 3.

Adjusted HRs for adverse outcomes after adjustment for Clinical (model 1), Clinical + CRP (model 2), and Clinical + Echocardiographic variables (model 3).

OUTCOME	Model 1*	p value	Model 2†	p value	Model 3‡	p value
All Cause Mortality
- Quartile I vs IV	2.1(1.3–3.3)	0.003	2.0(1.2–3.2)	0.004	1.9(1.0–3.5)	0.04
- Per SD ↓ in log telomere length	1.3(1.1–1.5)	0.005	1.2(1.1–1.4)	0.009	1.2(1.0–1.5)	0.12
HF Hospitalization
- Quartile I vs IV	2.1(1.1–3.8)	0.02	2.0(1.1–3.7)	0.03	2.6(1.1–6.0)	0.03
- Per SD ↓ in log telomere length	1.3(1.0–1.5)	0.04	1.2(1.0–1.5)	0.06	1.4(1.0–1.9)	0.03
CV Events (MI, Stroke, or CV Death)
- Quartile I vs IV	1.7(1.0–3.0)	0.07	1.7(0.9–2.9)	0.08	1.7(0.9–3.5)	0.12
- Per SD ↓ in log telomere length	1.1(0.9–1.4)	0.20	1.1(0.9–1.4)	0.22	1.1(0.9–1.4)	0.33

^*Adjusted for Age, Gender, Ethnicity, LDL Cholesterol, HDL Cholesterol, Systolic Blood Pressure, Diastolic Blood Pressure, BMI, Stroke, Smoking, Diabetes, CHF

^†Adjusted for all variables in Model 1 + Log CRP

^‡Adjusted for all variables in Model 1 + LVEF, Diastolic Dysfunction