Table 4.

Clusters where a significant difference of the CBF-atrophy mismatch measure between AD subjects and controls was detected. An increase means greater GM density decrease than CBF decrease in AD. A decrease means greater CBF decrease than GM density decrease.

Decreases	N voxels	Max z	Max z position	Anatomic Locations	%
Cluster 1	38475	4.73	−44, −8, −38	Temporal_Inf_R	6.95
				Temporal_Inf_L	6.85
				Temporal_Mid_R	5.77
				Occipital_Mid_L	5.48
				Precuneus_R	4.64
				Precuneus_L	4.5
				Temporal_Mid_L	4.41
				Angular_R	4.07
				Occipital_Mid_R	3.97
				Parietal_Sup_R	3.15
				Parietal_Sup_L	2.85
				Angular_L	2.26
				Parietal_Inf_L	2.24

Increases	N voxels	Max z	Max z position	Anatomic Locations	%
cluster 1	13046	4.32	38, −38, −2	Caudate_R	6.02
				Temporal_Pole_Sup_R	5.29
				Hippocampus_R	4.78
				Parahippocampal_R	4.57
				Hippocampus_L	4.32
				Caudate_L	3.27
				Parahippocampal_L	3.25
				Temporal_Pole_Sup_L	3.09
				Temporal_Sup_R	3.09
				Temporal_Sup_L	3.09
				Cingulum_Ant_R	2.41