Table 3.
Finding | Group | Preischemia | 120 min of ischemia | 15 min after reperfusion | 60 min after reperfusion |
---|---|---|---|---|---|
Histologic abnormality | |||||
Sinusoidal congestion | Control | 0 | 1.0 ± 0.15 | 1.4 ± 0.31 | 2.0 ± 0.21 |
Aw | 0.2 ± 0.2 | 1.0 ± 0 | 1.6 ± 0.24 | 1.6 ± 0.24 | |
Sinusoidal derangement | Control | 0 | 1.5 ± 0.17 | 1.3 ± 0.15 | 2.1 ± 0.1 |
Aw | 0 | 1.2 ± 0.2 | 1.6 ± 0.24 | 1.8 ± 0.2 | |
Ischemic hepatocyte injury | Control | 0 | 0 | 1.1±0.18 | 1.9 ± 0.18 |
Aw | 0 | 0 | 0.6 ± 0.24 | 1.0 ± 0.32* | |
Hepatocyte necrosis | Control | 0 | 0 | 0.1 ± 0.1 | 1.3 ± 0.15 |
Aw | 0 | 0 | 0 | 0† | |
Total score | Control | 0 | 2.5 ± 0.22 | 3.8 ± 0.42 | 7.3 ± 0.33 |
Aw | 0.2 ± 0.2 | 2.2 ± 0.2 | 3.8 0.73 | 4.4 ± 0.6† | |
Number of PMNs | Control | 16.7 ± 2.2 | 15.7 ± 2.2 | 39.4 ± 5.5 | 57.2 ± 6.4 |
Aw | 17.3 ± 3.4 | 18.2 ± 4.2 | 22.5 ± 5.2 | 22.3 ± 3.2* |
p < 0.05 versus control value.
p < 0.01 versus control value.
Aw, AwETN40; PMN, polymorphonuclear neutrophil.