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. 2009 May 8;284(19):12609–12621. doi: 10.1074/jbc.M901204200

FIGURE 2.

FIGURE 2.

Induction of Mt1 by arsenic requires MTF1. A, Nrf2 WT and KO cells were treated with tBHQ (30 μm), or As3+ (1, 5 and 10 μm) for 5 h. Total RNA was blotted with Mt1, Nqo1, and actin riboprobes. B, MTF1 WT, MTF1 KO, and MTF1 KO cells stably transfected with pMTF11–675 were treated with As3+ (10 μm) for 5 h. Total RNA was blotted for Mt1, Ho1, and actin mRNA expression.