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. 2009 May 8;284(19):12622–12632. doi: 10.1074/jbc.M900556200

TABLE 1.

Summary for ubiquitination of S5a by E2/E3 pairs tested in this study

“Yes” indicates that rapid ubiquitination of S5a was observed. “No” indicates that little or no ubiquitination of S5a was observed.

E3 type
E3
E2 type
Class I
Class II
Hetero-dimeric E2
E2 UbcH5 Ubc4 UbcH7 UbcH1 UbcH13/Uev1a
U-box CHIP Yes No
Monomeric Ring MuRF1 Yes No No
Siah2 Yes
Mdm2 Yes
Parkin Yes
Oligomeric Ring SCFβTRCP1 Yes
APC Yes
HECT E6AP Yes
Nedd4 Yes Yes