TABLE 2.

Interactions observed at the interface between UvrA and UvrB interaction domains

UvrA residues		UvrB residues		Distancea	Water-mediated
				Å
Arg170	NH1	Thr231	O	3.6	No
Lys171	O	Arg194	NH1	2.8, 3.5	Yes
Gly173	O	Arg196	NH2	2.8	No
Arg176	NH1	Glu215	OE1	3.4	No
		Glu222	OE2	3.2	No
		Asp198	O	3.1, 3.2	Yes
		Glu215	OE1	3.2, 2.6	Yes
		Phe216	N	3.1, 3.1	Yes
		Phe216	O	3.1, 2.8	Yes
		Glu222	OE2	3.2, 2.7	Yes
	NH2	Asp198	OD1	3.0	No
		Asp198	OD2	3.4	No
		Asp198	OD1	2.9, 2.7	Yes
		Asp198	OD2	2.9, 3.3	Yes
		Asp198	O	2.7, 3.2	Yes
		Phe216	N	2.7, 3.1	Yes
		Phe216	O	2.7, 2.8	Yes
Glu185	OE1	Arg223	NH2	3.4	No
	OE2	Arg223	NH1	2.8	No
		Arg223	NH2	3.4	No
Val204	O	Arg196	O	2.7, 2.8	Yes
Arg206	NE	Asp198	OD2	2.8	No
	NH1	Glu222	OE1	2.9, 2.6	Yes
		Glu222	OE2	2.9, 3.2	Yes
	NH2	Asp198	OD2	3.4	No
		Phe216	O	3.0	No
		Glu222	OE2	2.7	No
		Asp198	O	3.5, 3.2	Yes
		Phe216	N	3.5, 3.1	Yes
		Phe216	O	3.5, 2.8	Yes
	O	Asp198	OD2	2.6, 2.8	Yes
		Phe216	O	2.6, 3.4	Yes
Arg216	Stacking	Arg169	Stacking		No
	NH1	Arg169	N	3.1, 2.9	Yes
Asp219	OD2	Arg183	NH2	2.9	No
		Arg169	NH2	2.8, 3.0	Yes
		Gly197	N	2.7, 3.1	Yes
Ser220	OG	Arg169	NH2	2.8, 3.0	Yes

^aFor water-mediated contacts, the two numbers listed are the distances from the water to UvrA and UvrB, respectively