FIGURE 7.

Robust immune responses in CD45^62% mice challenged with B. anthracis. A, schematic diagram of time line study for CD45^100% and CD45^62% mice not infected or infected with Ames B. anthracis spores. At each time point (t = 0, 6, 24, 42 h), four mice/group were euthanized, various tissues were harvested, and plasma was collected. B, splenocytes isolated from mice euthanized at time 0, 6, 24, and 42 h post-B. anthracis challenge were stained for cell surface and activation markers and analyzed by flow cytometry. The data represent the averages of four mice/group/time points ±S.E. C, blood cells collected from mice euthanized at time 0, 6, 24, and 42 h post-B. anthracis infection were stained for cell surface and activation markers and analyzed by flow cytometry. The data represent the averages of four mice/group/time point and ±S.E.