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ATO-induced apoptosis in four human myeloma cell lines. U266, MM.1s, 8226/S, and KMS11 were treated for 6, 24, and 48 h with 2μm ATO. Viability was measured by Annexin-V-FITC/PI staining. Percent (%) of control viability, as percent of Annexin-V-negative cells, was plotted versus time (h). The data are presented as the mean ± S.D. of eight independent experiments.
