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Tumor pharmacokinetics of free doxorubicin versus liposomal doxorubicin formulations
| Formulation (2 mg/kg) | Tumor AUC0–48 h | Nucleus AUC0–48 h |
|---|---|---|
| μg·h/g | μg·h/g | |
| Free doxorubicin | 10.23 | 3.68 |
| Liposomal doxorubicin | 31.25 | 6.71 |
| PIVO-8-LD | 49.63 | 14.76 |
| PIVO-24-LD | 49.49 | 13.94 |
