Table 2.
Human genes isolated in an SOS screen of 65,000 transformants
| Genes | Isolates | Description |
|---|---|---|
| Ku70 | 1 | End-binding protein and putative ATP-dependent helicase II |
| Ligase | 1 | DNA ligase IV |
| RNA polymerase | 1 | Poly(A) polymerase |
| HSP90C-Ter | 2 | Terminal homology to HSP90 |
| HSP105 | 1 | Heat shock protein |
| XKLP2 homolog | 2 | Homolog of Xenopus centrosomal kinesin-like protein |
| MNS1 homolog | 1 | Homolog of mouse meiosis nuclear structural protein |
| Rabin3 homolog | 1 | Rat homolog of Ras-interacting protein |
| hTAFII18 | 1 | TFIID subunit |
| P2P-R homolog | 1 | Homolog of mouse potential proliferation protein-related |
| Kanadaptin homolog | 1 | Homolog of mouse kanadaptin |
| Annexin-binding protein | 3 | Homolog of mouse annexin-binding proteins |
| RAD50 homolog | 1 | Limited homology to yeast RAD50 |
| Unknown | 4 | Cross-reacts with antibodies to parathyroid hormone |
| Unknowns | – | 37 different cDNAs of unknown function |
There were 58 total isolates, and 51 total unique isolates (based on sequencing).