Table 3.
Growth response of strains containing human genes that induce the SOS response
| cDNA isolate | Size of human protein,* aa | Predicted size of coded protein† | Growth of recA strain‡ |
|---|---|---|---|
| Ku70 | 609 | 596 | No |
| DNA ligase IV | 844 | 192 | Yes |
| Poly(A) polymerase | 652 | 86 | Yes |
| HSP90C-Ter | NA§ | NA | Yes |
| HSP105 | 858 | 237 | No |
| XKLP2 homolog | NA | 509 | No |
| MNS1 homolog | 491 | 440 | No |
| Rabin3 homolog | 460 | 289 | Yes |
| hTAFII18 | 124 | 114 | No |
| P2P-R homolog | NA | 366 | No |
| Kanadaptin | NA | 484 | No |
| Annexin-binding protein (APB-7) | NA | 94 | No |
| RAD50 homolog | NA | NA | No |
*
Amino acids in reported full-length proteins.
†
Amino acids starting at the C-terminal end. Predicted sizes were determined by partial DNA sequencing and alignments to known homologs.
‡
Growth of isogenic recA strain when cDNA expressed.
§
NA (not applicable) because these genes were first isolated in this study.