Table 2.
Outcomes associated with black race, compared to white racea
| Unadjusted | Case-mix adjusted | Case-mix + laboratory + medications adjusted | |
|---|---|---|---|
| Predialysis all-cause mortality Hazard Ratio (95% CI) | 0.75 (0.59, 0.95) | 1.02 (0.80, 1.31) | 1.03 (0.80, 1.34) |
| ESRD Hazard Ratio (95% CI) | 1.64 (1.28, 2.12) | 1.42 (1.08, 1.86) | 1.06 (0.78, 1.43) |
| eGFR slope ml/min/1.73m2/yr (95% CI) | −0.3 (−0.7, 0.1) | −0.2 (−0.6, 0.3) | −0.1 (−0.6, 0.3) |
a
Fixed end points (mortality and ESRD) were examined in parametric survival models, and slopes were examined in multilevel mixed-effects models for change. Models we adjusted as indicated for case mix (age, diabetes mellitus, cardiovascular disease, smoking status, and blood pressure), baseline laboratory values (estimated glomerular filtration rate [except for slope analyses], serum albumin, bicarbonate, white blood cell count, percentage of lymphocytes in the white blood cell count, blood hemoglobin, 24 h urine protein) and medication use (calcitriol, phosphate binders and statins).
ESRD, end stage renal disease; eGFR, estimated glomerular filtration rate.