Table 5.

Areas under the curve (AUCs) for normalized urinary biomarkers at various time points^a

	Time after CPB
	Pre-OP	Immediately After	3 h	18 h	24 h
AKI (n = 36)
KIM-1	0.61 (0.51 to 0.72)	0.68 (0.58 to 0.78)	0.65 (0.54 to 0.75)	0.60 (0.49 to 0.71)	0.59 (0.47 to 0.70)
NAG	0.56 (0.46 to 0.67)	0.61 (0.50 to 0.71)	0.63 (0.51 to 0.73)	0.64 (0.52 to 0.74)	0.56 (0.44 to 0.67)
NGAL	0.55 (0.45 to 0.66)	0.59 (0.48 to 0.69)	0.65 (0.54 to 0.76)	0.70 (0.59 to 0.80)	0.59 (0.47 to 0.70)
Combined	0.63 (0.52 to 0.73)	0.75 (0.65 to 0.84)b	0.78 (0.68 to 0.87)c	0.70 (0.58 to 0.79)	0.68 (0.56 to 0.78)
Delta Scr (%)		0.67 (0.56 to 0.77)			0.83 (0.74 to 0.90)
Early AKI (n = 16)
KIM-1	0.72 (0.60 to 0.82)	0.79 (0.67 to 0.88)d	0.73 (0.60 to 0.83)	0.69 (0.56 to 0.80)	0.71 (0.57 to 0.83)
NAG	0.58 (0.45 to 0.69)	0.60 (0.47 to 0.71)	0.59 (0.46 to 0.71)	0.65 (0.52 to 0.77)	0.54 (0.40 to 0.68)
NGAL	0.55 (0.42 to 0.67)	0.51 (0.38 to 0.63)	0.58 (0.45 to 0.70)	0.68 (0.56 to 0.79)	0.64 (0.50 to 0.77)
Combined	0.75 (0.63 to 0.85)	0.80 (0.69 to 0.89)b	0.84 (0.72 to 0.92)e	0.83 (0.72 to 0.92)c	0.78 (0.65 to 0.88)f
Delta Scr (%)		0.72 (0.60 to 0.82)			1.00 (0.95 to 1.00)
Late AKI (n = 20)
KIM-1	0.54 (0.42 to 0.65)	0.61 (0.49 to 0.72)	0.60 (0.47 to 0.71)	0.54 (0.41 to 0.66)	0.54 (0.40 to 0.67)
NAG	0.55 (0.43 to 0.67)	0.62 (0.51 to 0.74)	0.65 (0.52 to 0.76)	0.62 (0.50 to 0.74)	0.54 (0.41 to 0.67)
NGAL	0.56 (0.44 to 0.67)	0.66 (0.54 to 0.76)	0.71 (0.59 to 0.82)	0.72 (0.60 to 0.82)	0.62 (0.48 to 0.74)
Combined	0.54 (0.42 to 0.66)	0.72 (0.60 to 0.82)	0.74 (0.62 to 0.84)	0.59 (0.46 to 0.71)	0.65 (0.52 to 0.77)
Delta Scr (%)		0.64 (0.52 to 0.75)			0.70 (0.58 to 0.80)

^aValues are AUC (95% confidence interval for AUC).

^bP < 0.05 versus NGAL, NAG.

^cP < 0.05 versus KIM-1, NAG.

^dP < 0.05 versus NGAL.

^eP < 0.05 versus KIM-1, NAG, NGAL.

^fP < 0.05 versus NAG.