Table 2.
Treatment characteristics and clinical outcomes of PD-associated peritonitis caused by Pseudomonas or other organisms in Australia, 2003 through 2006. Results are expressed as number (%) or median days [interquartile range]a
| Outcome | Pseudomonas Peritonitis (n = 191 Episodes) | Non-Pseudomonas Peritonitis (n = 3403 Episodes) | P |
|---|---|---|---|
| Treatment | |||
| change to second antibiotic regimen (n [%]) | 126 (66) | 1884 (55) | 0.005 |
| time to second antibiotic regimen (d; median [IQR]) | 2.00 (1.00 to 4.00) | 3.00 (2.00 to 5.00) | 0.030 |
| change to third antibiotic regimen (n [%]) | 48 (25) | 449 (13) | <0.001 |
| time to third antibiotic regimen (d; median [IQR]) | 6.00 (4.00 to 11.00) | 7.00 (4.00 to 10.00) | 0.400 |
| total antibiotic treatment duration (d; median [IQR]) | 16.00 (9.75 to 23.00) | 14.00 (8.00 to 19.00) | 0.001 |
| Relapse (n [%]) | 17 (9) | 485 (14) | 0.040 |
| Hospitalization | |||
| n (%) | 150 (79) | 2354 (69) | 0.006 |
| duration (d; median [IQR]) | 9.00 (5.00 to 20.00) | 6.00 (3.00 to 11.00) | <0.001 |
| Catheter removal | |||
| n (%) | 84 (44) | 691 (20) | <0.001 |
| time to occurrence (d; median [IQR]) | 5.50 (3.00 to 11.00) | 6.00 (3.00 to 13.00) | 0.400 |
| Temporary hemodialysis | |||
| n (%) | 20 (10) | 132 (4) | <0.001 |
| time to occurrence (d; median [IQR]) | 7.50 (4.25 to 12.50) | 6.00 (3.00 to 11.50) | 0.500 |
| duration (d; median [IQR]) | 73.50 (51.00 to 109.50) | 67.00 (20.50 to 103.00) | 0.300 |
| Permanent hemodialysis | |||
| n (%) | 66 (35) | 569 (17) | <0.001 |
| time to occurrence (d; median [IQR]) | 6.00 (4.00 to 11.75) | 7.00 (4.00 to 13.00) | 0.700 |
| Death | |||
| n (%) | 6 (3) | 76 (2) | 0.400 |
| time to death (d; median [IQR]) | 19.00 (5.00 to 26.00) | 11.00 (3.00 to 22.25) | 0.400 |
a
IQR, interquartile range.