Table 2.
MV-shuttled mRNA involved in transcription, cell proliferation, and immune regulation
| Functional Category | mRNA | Description |
|---|---|---|
| Transcription factors | CLOCK | Clock homolog (mouse) |
| IRF6 | Interferon regulatory factor 6 | |
| LHX6 | LIM homeobox 6 | |
| RAX2 | Retina and anterior neural fold homeobox 2 | |
| TCFP2 | Transcription factor CP2 | |
| BCL6B | B-cell CLL/lymphoma 6, member B | |
| DNA/RNA binding | HMGN4 | High mobility group nucleosomal binding domain 4 |
| TOPORS | Topoisomerase I binding, arginine/serine rich | |
| ESF1 | Nuclear pre-rRNA processing protein | |
| POLR2E | Polymerase (RNA) II (DNA-directed) polypeptide E, 25 kDa | |
| ELP4 | Elongation protein 4 homolog | |
| HNRPH2 | Heterogeneous nuclear ribonucleoprotein H2 | |
| Cell Cycle | SENP2 | SUMO1 |
| RBL1 | Retinoblastoma-like 1 (p107) | |
| CDC14B | CDC14 cells division cycle 14 homolog B | |
| S100A13 | S100 calcium binding protein A13 | |
| Receptors | CEACAM5 | Carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLEC2A | C-type lectin domain family 2, member A | |
| CXCR7 | Chemokine (C-X-C motif) receptor 7 | |
| Enzymes/metabolism | ADAM15 | ADAM metallopeptidase domain 15 |
| FUT3 | Fucosyltransferase 3 | |
| ADM2 | Adrenomedullin 2 | |
| LTA4H | Leukotriene A4 hydrolase | |
| BDH2 | 3-Hydroxybutyrate dehydrogenase, type 2 | |
| RAB5A | RAB5A, member RAS oncogene family | |
| Immune regulation | CRLF1 | Cytokine receptor-like factor 1 |
| IL1RN | Interleukin 1 receptor antagonist | |
| MT1X | Metallothionein 1X | |
| Cytoskeleton | DDN | Dendrin |
| MSN | Moesin | |
| CTNNA1 | Catenin (cadherin-associated protein) | |
| Extracellular matrix | COL4A2 | Collagen type IV, alpha 2 |
| IBSP | Bone sialoprotein II |