Table 2. Comparison of lectin binding of drusen, RPE, Bruch’s membrane, and photoreceptors in AMD.
| Lectin | Drusen | RPE | Bruch’s | RC | CC | Rod OS | Cone OS | RM | CM |
|---|---|---|---|---|---|---|---|---|---|
| CON A |
3 |
3 |
3 |
2 |
0 |
3 |
3 |
3 |
3 |
| PSA |
3 |
3 |
3 |
1 |
0 |
3 |
3 |
3 |
3 |
| ePHA |
3 |
3 |
3 |
1 |
0 |
3 |
3 |
3 |
3 |
| lPHA |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| SNA-1 |
4 (4) |
4 (4) |
4 (4) |
1 (0) |
0 (0) |
4 (0) |
4 (0) |
0 (0) |
0 (0) |
| MAA |
3 (1) |
3 (0) |
0 (0) |
1 (0) |
0 (0) |
3 (3) |
3 (3) |
3 (3) |
3 (3) |
| LFA |
3 (0) |
1 (0) |
0 (0) |
1 (0) |
1 (0) |
3 (0) |
3 (0) |
1 (0) |
1 (0) |
| WGA |
2 (2) |
2 (0) |
2 (0) |
0 (0) |
0 (0) |
2 (0) |
2 (0) |
2 (0) |
2 (0) |
| DSA |
4 |
4 |
4 |
0 |
0 |
3 |
3 |
2 |
2 |
| STA |
4 |
4 |
4 |
1 |
1 |
3 |
3 |
1 |
2 |
| SBA |
0 (2) |
0 (2) |
0 (2) |
0 (0) |
0 (0) |
0 (1) |
0 (1) |
0 (0) |
0 (0) |
| DBA |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| WFA |
0 |
0 |
0 |
0 |
0 |
0 |
3 |
0 |
0 |
| AHA |
0 (2) |
0 (2) |
0 (1) |
0 (1) |
0 (0) |
0 (3) |
2 (3) |
0 (3) |
2 (3) |
| MPA |
2 |
0 |
0 |
1 |
1 |
2 |
2 |
3 |
3 |
| Jac |
3 (2) |
3 (2) |
3 (2) |
3 (2) |
3 (2) |
4 (3) |
4 (3) |
4 (3) |
4 (3) |
| BSA-1B4 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| ECA |
0 (3) |
0 (2) |
0 (2) |
0 (0) |
0 (0) |
0 (3) |
0 (3) |
0 (3) |
0 (3) |
| UEA-1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Key: 0 indicates no binding, 1indicates weak, 2=moderate, 3=moderately strong and 4=intense binding; results in brackets indicate intensity of binding after neuraminidase pretreatment. Abbreviations: RC is rod cytoplasm, CC is cone cytoplasm, RM is rod cell membrane, CM is cone cell membrane, OS is outer segments.