Table 5. Distribution of APOE genotype and allele frequencies in patients with POAG and matched controls.
| Genotype/Allele | Open angle glaucoma (n=60) | Controls (n=130) | p value | RR | EF*/PF |
|---|---|---|---|---|---|
|
ε3/ε4 |
7 (11.66) |
11 (8.4) |
0.59 |
1.428 |
0.113* |
|
ε4/ε4 |
3 (5.00) |
00 |
0.03 |
- |
- |
|
ε3/ε3 |
50 (83.33) |
119 (91.5) |
0.13 |
0.462 |
0.255 |
|
ε4 |
13 (10.83) |
11 (4.2) |
0.02 |
2.75 |
0.034* |
| ε3 | 107 (89.16) | 249 (95.7) | 0.02 | 0.363 | 0.034 |
Number of subjects=n; values are indicated as n (%). Values with asterisk (last column) correspond to etiological fraction (EF) while values without asterisk indicate protective fraction (PF).