Table 2. mRNA expression of cytokines in the retina: MIP-2, IL-6, TNF-α.
| MIP-2 | |||
|---|---|---|---|
|
3 h |
12 h |
24 h |
7 days |
|
n=7 |
n=10 |
n=4 |
n=7 |
| 0.65 |
2.3 |
3.93 |
0 |
| −3.93 |
4.24 |
29.04 |
0.36 |
| 0.44 |
−0.3 |
2.11 |
0.03 |
| 0.08 |
35.3 |
14.12 |
0.39 |
| −1.58 |
5.54 |
0.2 |
|
| 0.28 |
11 |
−20.4 |
|
| 0.21 |
20.25 |
0.16 |
|
| 0.49 |
11.43 |
0.6 |
|
| 0.34 |
11.43 |
−1.95 |
|
| 3.32 |
|||
| 49.69 |
|||
|
IL-6 | |||
|
3 h |
12 h |
24 h |
7 days |
|
n=6 |
n=8 |
n=3 |
n=7 |
| 0.68 |
−1.15 |
56.1 |
0 |
| 0.6 |
21.86 |
182.91 |
0 |
| −16.5 |
17.21 |
47.83 |
0 |
| 0.41 |
10.2 |
−1.36 |
0 |
| −3.14 |
38.85 |
0.4 |
|
| −3.36 |
25.36 |
0.09 |
|
| 0.315 |
21.18 |
0.77 |
|
| 0.6 |
30.06 |
||
| 0.47 |
16.22 |
||
|
TNF-α | |||
|
3 h |
12 h |
24 h |
7 days |
|
n=5 |
n=7 |
n=4 |
n=6 |
| −0.008 |
−0.59 |
2.52 |
0.25 |
| 5.52 |
1.55 |
4.87 |
1.87 |
| 1.56 |
−0.63 |
2.24 |
0.37 |
| 1.01 |
13.74 |
3.49 |
0.15 |
| 7.97 |
2.11 |
2.58 |
|
| 7.62 |
1.25 |
1.42 |
|
| −0.11 |
1.54 |
||
| −0.43 |
1.94 |
||
| −0.54 |
−0.83 |
||
| −0.34 |
|||
| 22 | |||
Relative expression of mRNA of cytokines in the retina of the ischemic eyes, as compared to the left untreated control eye (MIP-2, IL-6, TNF-α), at different time intervals from CRAO induction. The marked numbers represent extreme points which did not follow the trend determined by the majority of samples at each time point. The number of samples at each time point refers to the samples which comprise the majority determining the trend.