TABLE 1.
Cardiovascular Medication Use and Prevalence of Vascular Conditions in Dementia Progression Study
| Number of Participants (%) |
Age (years) |
% Female |
Education (years) |
Baseline MMSE |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Medication Use | Yes | No | Yes | No | Yes | No | Yes | No | Yes | No |
| Statins | 31 (15%) | 183 (85%) | 83.0 (6.2) | 85.7 (6.5) | 58 | 71 | 13.9 (2.6) | 13.2 (2.8) | 22.6 (3.7) | 21.4 (4.7) |
| Beta-Blockers | 33 (15%) | 181 (85%) | 86.3 (6.6) | 85.2 (6.6) | 79 | 67 | 12.9 (2.2) | 13.3 (2.9) | 22.4 (3.5) | 21.5 (4.7) |
| ACE Inhibitors | 32 (15%) | 182 (85%) | 84.4 (5.9) | 85.5 (6.6) | 59 | 71 | 13.3 (3.7) | 13.3 (2.6) | 21.9 (5.0) | 21.6 (4.5) |
| Calcium Channel Blockers | 36 (16%) | 179 (84%) | 85.8 (5.7) | 85.3 (6.7) | 71 | 69 | 13.5 (3.1) | 13.2 (2.8) | 21.8 (5.1) | 21.6 (4.5) |
| Diuretics | 42 (20%) | 172 (80%) | 86.6 (6.3) | 85.0 (6.6) | 81 | 66 | 13.1 (2.2) | 13.3 (3.0) | 22.3 (4.2) | 21.4 (4.6) |
|
Angina (%) |
MI (%) |
Stroke (%) |
Diabetes (%) |
|||||||
| Medication Use | Yes | No | Yes | No | Yes | No | Yes | No | ||
|
| ||||||||||
| Statins | 32.3 | 9.3 | 38.7 | 13.7 | 19.4 | 4.4 | 35.5 | 14.2 | ||
| Beta-Blockers | 27.3 | 9.9 | 24.2 | 16.0 | 6.0 | 6.6 | 21.2 | 16.6 | ||
| ACE Inhibitors | 9.4 | 13.2 | 34.4 | 14.3 | 9.4 | 6.0 | 37.5 | 13.7 | ||
| Calcium Channel Blockers | 17.1 | 11.7 | 25.7 | 15.6 | 11.4 | 5.5 | 22.9 | 16.2 | ||
| Diuretics | 21.4 | 10.5 | 19.0 | 16.9 | 9.5 | 5.8 | 23.8 | 15.7 | ||
Notes: N = 216 participants assessed at baseline. Statistic used was Student’s t (df = 212) for continuous variables and Pearson’s χ2(1) for categorical variables. Continuous variables are expressed as mean (SD) or N (%). Variables that differed significantly (p < .05) by medication use are in bold face.